Custom Url or Url Re-write

 I have a requirement to show the custom url to the user
i.e  http://localhost:9503/Profile.aspx?ProfileID=1  [I should be able to show http://localhost:9503/Profile.aspx/1 or http://localhost:9503/Profile.aspx/ProfileUserName/ID
which ever part is easy using asp.net 4.5 C# any help
simple redirect code
<div> <a href="Profile.aspx?ProfileID=1" target="_blank">Profile one</a> <a href="Profile.aspx?ProfileID=2" target="_blank">Profile two</a> <a href="Profile.aspx?ProfileID=3" target="_blank">Profile Three</a> </div> protected void Page_Load(object sender, ...