Not able to open word programatically due to permissions issues(maybe)

Team,
Working on a web app installed on 64 bit Windows 2008 OS and using 64 bit office 2010.
I have tried hard to find a fix for this. I am not able to open a word file programatically . I get this error as per stack trace
System.Runtime.InteropServices.COMException (0x800A175D): Could not open macro storage.
   at Microsoft.Office.Interop.Word.Documents.Open(Object& FileName, Object& ConfirmConversions, Object& ReadOnly, Object& AddToRecentFiles, Object& PasswordDocument, Object& PasswordTemplate, Object& Revert, Object& WritePasswordDocument, Object& WritePasswordTemplate, Object& Format, Object& Encoding, Object& Visible, Object& OpenAndRepair, Object& DocumentDirection, Object& NoEncodingDialog, Object& XMLTransform)
   at Edenbrook.Hindsite.BL.DocumentHelpers.Word.WordDoc.Open(String strFileName).......
 
This basi ...