Uncaught Error: ASP.NET Ajax client-side framework failed to load.

Ajax tool kit is not working . when i am using Calender, ajax uploader its not working.
when am checking browser view inspect showing error like 
Uncaught SyntaxError: Unexpected token < ScriptResource.axd:3 Uncaught SyntaxError: Unexpected token < album:52 Uncaught Error: ASP.NET Ajax client-side framework failed to load. ScriptResource.axd:3 Uncaught SyntaxError: Unexpected token < ScriptResource.axd:3 Uncaught SyntaxError: Unexpected token < ScriptResource.axd:3 Uncaught SyntaxError: Unexpected token < ScriptResource.axd:3 Uncaught SyntaxError: Unexpected token < album:76 Uncaught ReferenceError: Sys is not defined album:462 Uncaught ReferenceError: Sys is not defined

Please give me solution :)