how to isolate and find reason for frozen state method

An ASPX C# code calls the Send() method of the Outlook.Application ActiveX. Sometimes the code goes into frozen state, while showing the hourglass mouse icon.
A break point just before, on, and after the calling the method, led us to find that the issue occurs when the method is called. Seems like something gets stuck or delays within the method. Since the method is part of the Office infrastructure, and since no error is issued, can u pls advise how to isolate the problem and find the reason for it ?
Just to clarify, this question was already asked on an office forum, with no potential answer, hence asked here for resolution. Kind thx,